Feng Li

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PhD in Coordination and Supramolecular Chemistry (2006), Instituto de Tecnologia Química e Biológica da Universidade Nova de Lisboa, Portugal.

Dr. Feng Li was appointed as a Lecturer in Chemistry at Western Sydney University in February 2012 and joins NICM as an Associate Member.

In 2007, Li took up a post-doctoral position at the University of Sydney (2007-2012), where he carried out full time research in the areas of metallo-supramolecular chemistry and inorganic materials chemistry.  Meanwhile, he was also appointed as an Honorary Associate in the School of Chemistry at the University of Sydney. He is also an Honorary Professor at Zhengzhou University, College of Chemistry and Molecular Engineering.

Research Strengths

Dr Li's research spans a broad range of organic and inorganic synthetic chemistry, analytical techniques and chemical biology in the field of metallo-supramolecular system. Synthesis strategies in directed assembly procedures, hierarchical or stepwise syntheses and template controls are explored to construct innovative finite nanometre-scale assemblies that include four categories: (1) mononuclar, dinuclear and trinuclear coordination complexes (2) cones, cylinders, helicates and circular helicates (3) coordination cage and capsule systems (4) metallo-supramolecular interlocked/Intertwined structures. New advanced multifunctional materials are developed for potential applications in chemistry (molecular recognition, magnetism, redoxactive, photoactive, conductive, catalytic and non-linear optical properties) and biology (DNA binding, drug delivery, metal-based anti-cancer drugs and traditional Chinese medicine (TCM) active ingredient metal based anticancer agents).

Research Projects include: 

  • Metal Directed Assembly of Discrete Supramolecular Systems
  • Discrete Interlocked/Intertwined Metallo-Supramolecular Assemblies
  • Anion Detection Using Metal-based Complexes
  • Molecular Recognition Using Macrocyclic Compounds

Complementary medicines

The research work in developing new type of Traditional Chinese medicine (TCM) active ingredient metal based anticancer agents is investigated in the joint project with A/Prof. Chun Guang Li. Because the TCM-metal based anticancer agents represent the other approach of organisation which may lead to novel therapies by the cooperative effect of TCM and metal complexes, and generate a novel strategy that can bring the combinative activities of both TCM and metal complexes to rational cancer therapy.

 Awards

2002 – 2006 PhD Scholarship of FCT (Fundação para a Ciência e a Tecnologia), the most prestigious PhD scholarship awarded within Portugal.

2000 Chosen to enter WYRE (Worldwide Young Researchers for the Environment) Competition in Germany.

1999 – 2001 Excellence Prize in the Postgraduate Student Fellowship in every semester. (This honour is conferred to the top 1% of students)

1999 Direct entry to Graduate Programs at Zhengzhou University, qualification examination waived due to my excellent grades in chemistry

1998 Golden Prize in the National Chemistry Experiment Competition for University Students (6th place nationwide in China from approx. 300 selected applicants from most top universities of China).

1995 – 1999 Outstanding Undergraduate Student Fellowship in every semester. (This honour is conferred to the top 5% of students).

1995 Direct entry to Undergraduate Programs at Zhengzhou University, qualification examination waived due to excellent grades in chemistry.

Links and Memberships

Dr Li is regularly asked to act as a peer-reviewer for journals including Dalton Trans, Cryst Eng Comm, RSC Advances, New Journal of Chemistry, Physical Chemistry Chemical Physics and Synthetic Commun. In 2012, he acted as a conference committee member for a special international conference, 4th International Symposium on Coordination & Supramolecular Chemistry. In 2014 he also has been appointed as a guest editor for a special issue of J. Incl. Phen. Mac. Chem. in commemoration of 70th Birthday of Prof. Jack M. Harrowfield and Prof. Jacques Vicens.

He is a chartered member (MRACI CCHEM) of the Royal Australian Chemical Institute (RACI) and a member of Society of Crystallographers in Australia and New Zealand (SCANZ), International Union of Pure and Applied Chemistry (IUPAC) and American Chemical Society (ACS).

Publications

Book Chapters

Harper BW, Li F, Beard R, Garbutcheon-Singh KB, Ng NS, Aldrich-Wright JR. Metal complexes and nucleic acid interactions. In: Schneider HJ, editor. Supramolecular Systems in Biomedical Field. Cambridge Royal Society of Chemistry; 2013. p. 260-99.

Gloe K, Gloe K, Wenzel M, Lindoy LF, Li F. Supramolecular chemistry in solvent extraction: Towards highly selective extractants and a better understanding of phase transfer phenomena. In: Moyer BA, editor. Ion Exchange and Solvent Extraction: A Series of Advances. Boca Raton/USA: CRC Press, Taylor & Francis Group; 2013.

Journal Articles

Reichel F, Clegg JK, Gloe K, Gloe K, Weigand JJ, Reynolds JK, et al. Self-assembly of an imidazolate-bridged feIII/cuII heterometallic cage. Inorg Chem. 2014;53(2):688–90. DOI: 10.1021/ic402686s.

Clegg JK, Li F, Jolliffe KA, Lindoy LF, Meehan GV, Parsons S, et al. Hierarchical self-assembly of discrete multinuclear assemblies from neutral dinuclear (bis-β-diketonato)metallocycles 'building blocks' and flexible linkages. Dalton Trans. 2013;42:14315-23. DOI: 10.1039/C3DT51531A.

Clegg JK, Li F, Lindoy LF. Di- tri- and Oligonuclear Platforms: Versatile components for use in metallo-supramolecular chemistry. Coordination Chemistry Reviews. 2013;257(17-18):2536-50. DOI: 10.1016/j.ccr.2013.01.006.

Lee M, Zali-Boeini H, Li F, Lindoy LF, Jolliffe KA. Synthesis of tris-(azacrown) ethers for carboxylic acid recognition. Tetrahedron. 2013;69:38-42. DOI: 10.1016/j.tet.2012.10.067.

Vasilescu IM, Bourne DJ, Clegg JK, Li F, Lindoy LF, Meehan GV. Comparative investigation of the interaction of Zn(II), Cd(II), Ag(I) and Pb(II) with dibenzo-substituted macrocyclic ligands incorporating both symmetrically and unsymmetrically arranged N, O and S donors: synthetic, solution and Xray studies. Supramol Chem. 2012;24(8):572-84. DOI: 10.1080/10610278.2012.688130.

Li F, Clegg JK, D'Alessandro DM, Goux-Capes L, Sciortino NF, Keene TD, et al. Self-assembled Co(II) molecular squares incorporating the bridging ligand 4,7-phenanthrolino-5,6:5',6'-pyrazine (ppz). Dalton Trans. 2011;40:12388-93. DOI: 10.1039/C1DT11254F.

Li F, Clegg JK, Kepert CJ. Structural diversity in coordination polymers constructed from a naphthalene-spaced dipyridyl ligand and iron(II) thiocyanate. J Incl Phenom Macro. 2011;71(3-4):381-8. DOI: 10.1007/s10847-011-0016-5.

Mateus P, Li F, Esteves CV, Delgado R, Brandão P, Félix V. Properties of metal complexes of a new dioxadiaza macrocycle containing a dibenzofuran unit and acetate pendant arms. Eur J Inorg Chem. 2011;2011(30):4700-8. DOI: 10.1002/ejic.201100612.

Vasilescu IM, Baldwin DS, Bourne DJ, Clegg JK, Li F, Lindoy LF, et al. Comparative investigation of the interaction of Zn(II), Cd(II), Ag(I) and Pb(II) with dibenzo-substituted macrocyclic ligands incorporating both symmetrically and unsymmetrically arranged N, O and S donors: synthetic, solution and X-ray studies. Supramol Chem. 2012;24(8):572-84. DOI: 10.1080/10610278.2012.688130.

Clegg JK, Li F, Jolliffe KA, Meehan GV, Lindoy LF. An expanded neutral M4L6 cage that encapsulates four tetrahydrofuran molecules. Chem Commun. 2011;47:6042-4. DOI: 10.1039/C1CC11167A.

Li F, Clegg JK, Lindoy LF, Macquart RB, Meehan GV. Metallosupramolecular self-assembly of a universal 3-ravel. Nature Comm. 2011;2:205. DOI: 10.1038/ncomms1208.

Li F, Clegg JK, Goux-Capes L, Chastanet G, D'Alessandro DM, Létard J-F, et al. A mixed-spin molecular square with a hybrid-[2x2]grid/metallocyclic architecture. Angew Chem Int Ed. 2011;50(12):2820-3. DOI: 10.1002/anie.201007409.

Li F, Clegg JK, Price D, Kepert CJ. Self-assembly of a metallomacrocycle templated by Iron(II). Inorg Chem. 2011:726-8. DOI: 10.1021/ic102350t.

Prior to 2011 Dr Li has 16 other journal articles.