Dennis Chang

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PhD, MSc
Executive Committee Member, NICM Health Research Institute
Professor of Pharmacology Research, NICM Health Research Institute
Associate Director Research, Engagement and Partnerships (Asia), NICM Health Research Institute
Health Hearts Research Program Lead, NICM Health Research Institute

DennisDennis Chang is a Professor of Pharmacology and lead of NICM's Healthy Hearts Research Program. Over the last 10 years he has developed a strong research agenda in the area of clinical and pharmacological studies of Chinese herbal medicine at NICM and Western Sydney University.

Professor Chang is a chief investigator for a number of significant clinical trials to evaluate complementary medicine interventions (herbal medicine, yoga and tai chi) for the treatment of dementia, mild cognitive impairment, coronary heart disease, metabolic syndrome and type 2 diabetes.

He has also led multiple laboratory-based pharmacological studies of herbal medicines to evaluate their pharmacokinetic/bioavailability profiles and mechanisms of action underlying the neuro and cardiac-protective effects of these medicines using a range of in vitro and in vivo models.

Professor Chang has attracted significant research funding from various external funding agencies, governments and industry, and from internal sources totalling over $6M. His research has been published in a broad range of high-quality peer-reviewed journals such as Cochrane Systematic Review (IF:6.032), Journal of Translational Medicine (IF:3.93), Clinical Pharmacology and Therapeutics (IF:7.093), British Journal of Pharmacology (IF:4.842), and Drug (IF4.343).

Professor Chang has a significant involvement in the strategic planning and development of NICM. He has also made exceptional contributions to the development of national and international research collaborations and has attracted partnerships with prestigious international and national universities, research organisations and pharmaceutical/herbal medicine industry.

Research focus

  • Pharmacology
  • Physiology and Pathophysiology
  • Pharmacokinetics/bioavailability
  • Clinical trials
  • Dementia and cognitive impairment
  • Diabetes and Metabolic disease

Awards and recognitions

  • Visiting Professor, Guangzhou Medical University
  • Coordinator of the South Pacific Chapter of the Consortium for Globalisation of Chinese Medicine
  • 1993-1995 Australian Postgraduate Award

Projects and grants

Professor Chang's research has been supported by numerous external funding agencies including federal and state governments, NHMRC, local and international industry, and professional associations. Over the last five years he has attracted eight successful external research grants totalling $4.7 million.

See a full list of past and current projects.(opens in a new window)


  • 1998 PhD in Pharmacology, The University of Sydney, Australia
  • Master in Science, The University of Sydney, Australia


For a full listing of publications please see: